Bioinformatics is an emerging field of science that is concerned with the management, analysis and visualization of the flood of data being generated in molecular and cellular biology, genomics and other areas of biology and biomedicine. Center for Integrated Bioinformatics focuses on a system approach to bioinformatics in which information at the gene, protein, cell, tissue, organ, and system level is integrated and interpreted for early detection, accurate diagnosis, and effective treatment of complex diseases such as cancer. The overall objective of the educational program is to train students in system approaches for the development of useful computational models of living systems and novel enabling informatics technologies in life sciences. See: Center for Integrated Bioinformatics at Drexel's School of Biomedical Engineering, Science and Health Systems, 'What is Bioinformatics?' and Glossary of biotechnology terms to get some basic idea about this emerging field of technology. See also: Guide to Selected Bioinformatics Internet Resources
Books Click on the links below to see what books are available in the library in some key areas related to Bioinformatics:
- Introducation and bioinformatics
- Systems and cell biology
- Human genome project
Electronic Books Click on the links below to access electronic books (Access only to Drexel faculty and students)
- Encyclopedia of ethical, legal, and policy issues in biotechnology [electronic resource]
- Encyclopedia of Biomaterials and Biomedical Engineering
- Encyclopedia of the Human Genome
- Gene Symbol and 'What is a gene'?.
Genetics Home Reference provides consumer-friendly gene summaries that include an explanation of each gene’s normal function and how mutations in the gene cause particular genetic conditions.
- Knovel: Engineering and Scientific Online References
Use databases below to find scholarly journal articles on the topic of your research project.
- ACM Guide to Computing Literature
- Annual Reviews
- Ei Compendex and INSPEC
- Google Scholar
- IEEE Xplore
- Science's STKE: Signal Transduction Knowledge Environment Web of Knowledge
Key Web Resources
- Nucleic Acids Research Collaboration The editors from Oxford Press and the journal Nucleic Acids Research (NAR) have joined forces with the UBC Bioinformatics Centre (UBiC) to ensure that all of the links from the Web Server special issues are listed in the Bioinformatics Links Directly.
- 20 Facts about the Human Genome
- DNA sequencing Technologies Key to the Human Genome Project
- Human Genome Collection Complete and comprehensive DNA sequence of the human genome as a freely available resource from Nature
- Human Genome Project at the Sanger Institute
- The Finished Human Genome - Wellcome To The Genomic Age
- BioGRID: The Biological General Repository for Interaction Datasets (BioGRID) is a public database that archives and disseminates genetic and protein interaction data from model organisms and humans (thebiogrid.org). BioGRID currently holds over 500,000 interactions curated from both high-throughput datasets and individual focused studies, as derived from over 30 000 publications in the primary literature
- NCBI - National Center for Biotechnology Information Established in 1988 as a national resource for molecular biology information, NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information - all for the better understanding of molecular processes affecting human health and disease.
- See: NCBI - National Center for Biotechnology Information
- Coffee Break: Tutorials for NCBI tools
- NCBI Handbook
- Human Genome Resources from NCBI
- NCBI - Genes and Disease Entrez Gene (NOTE: Entrez Gene is a searchable database of genes, from RefSeq genomes, and defined by sequence and/or located in the NCBI Map Viewer )
- OMIM - Online Mendelian Inheritance in Man (NOTE: This database is a catalog of human genes and genetic disorders authored and edited by Dr. Victor A. McKusick and his colleagues at Johns Hopkins and elsewhere, and developed for the World Wide Web by NCBI, the National Center for Biotechnology Information.)
- Examples of questions that can be answered with OMIM in Entrez . See Sample Searches to find answers to the examples of questions listed above. Ensembl (NOTE: Ensembl is a joint project between EMBL - EBI and the Sanger Institute to develop a software system which produces and maintains automatic annotation on selected eukaryotic genomes.)
- Entrez Global Query NCBI's Entrez Global Query is a cross-database search option that searches many Entrez databases at one time. The results list the number of records in each database that match your query, and provides links to those records. The Global Query search page also acts as a short Entrez database directory since each database is briefly described (select the question mark icon next to each database). (Source: Bioinformatics Research Guide from the University of California, Santa Cruz)