Bioinformatics is an emerging field of science that is concerned with the management, analysis and visualization of the flood of data being generated in molecular and cellular biology, genomics and other areas of biology and biomedicine.
Center for Integrated Bioinformatics focuses on a system approach to bioinformatics in which information at the gene, protein, cell, tissue, organ, and system level is integrated and interpreted for early detection, accurate diagnosis, and effective treatment of complex diseases such as cancer. The overall objective of the educational program is to train students in system approaches for the development of useful computational models of living systems and novel enabling informatics technologies in life sciences.
See: Center for Integrated Bioinformatics at Drexel's School of Biomedical Engineering, Science and Health Systems, 'What is Bioinformatics?' and Glossary of biotechnology terms to get some basic idea about this emerging field of technology.
Click on the links below to see what books are available in the library in some key areas related to Bioinformatics:
Click on the links below to access electronic books (Access only to Drexel faculty and students)
Encyclopedia of ethical, legal, and policy issues in biotechnology [electronic resource]
Encyclopedia of Biomaterials and Biomedical Engineering
Gene Symbol and 'What is a gene'?. Genetics Home Reference provides consumer-friendly gene summaries that include an explanation of each gene’s normal function and how mutations in the gene cause particular genetic conditions.
Knovel: Engineering and Scientific Online References
BioGRID: The Biological General Repository for Interaction Datasets (BioGRID) is a public database that archives and disseminates genetic and protein interaction data from model organisms and humans (thebiogrid.org). BioGRID currently holds over 500,000 interactions curated from both high-throughput datasets and individual focused studies, as derived from over 30 000 publications in the primary literature
Established in 1988 as a national resource for molecular biology information, NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information - all for the better understanding of molecular processes affecting human health and disease.
NCBI - National Center for Biotechnology Information
Bioinformatics and science primer
Human Genome Resources from NCBI
NCBI - Genes and Disease
(NOTE: Entrez Gene is a searchable database of genes, from RefSeq genomes, and defined by sequence and/or located in the NCBI Map Viewer )
OMIM - Online Mendelian Inheritance in Man
(NOTE: This database is a catalog of human genes and genetic disorders authored and edited by Dr. Victor A. McKusick and his colleagues at Johns Hopkins and elsewhere, and developed for the World Wide Web by NCBI, the National Center for Biotechnology Information.)
Examples of questions that can be answered with OMIM in Entrez . See Sample Searches to find answers to the examples of questions listed above.
(NOTE: Ensembl is a joint project between EMBL - EBI and the Sanger Institute to develop a software system which produces and maintains automatic annotation on selected eukaryotic genomes.)
Entrez Global Query
NCBI's Entrez Global Query is a cross-database search option that searches many Entrez databases at one time. The results list the number of records in each database that match your query, and provides links to those records. The Global Query search page also acts as a short Entrez database directory since each database is briefly described (select the question mark icon next to each database).
(Source: Bioinformatics Research Guide from the University of California, Santa Cruz)
Use databases below to find scholarly journal articles on the topic of your research project.
ACM Guide to Computing Literature
(Note: Wiley Interscience Blackwell Synergy is no longer functioning as of June 27, 2008. All content has been transferred to Wiley InterScience)
Ei Compendex and INSPEC
Science's STKE: Signal Transduction Knowledge Environment
Web of Knowledge
News and Recent Developments
Use the following databases to find information on breaking news in biomedical technologies in magazines and newspapers
Key Web Resources
About the Human Genome Project
Begun formally in 1990, the U.S. Human Genome Project was a 13-year effort coordinated by the U.S. Department of Energy and the National Institutes of Health. The project originally was planned to last 15 years, but rapid technological advances accelerated the completion date to 2003.
Bioinformatics Links Directory
The Bioinformatics Links Directory features curated links to molecular resources, tools and databases. The links listed in this directory are selected on the basis of recommendations from bioinformatics experts in the field.
Nucleic Acids Research Collaboration
The editors from Oxford Press and the journal Nucleic Acids Research (NAR) have joined forces with the UBC Bioinformatics Centre (UBiC) to ensure that all of the links from the Web Server special issues are listed in the Bioinformatics Links Directly.
Resources for Bioinformatics
Compilation of resources from the The Robert S Boas Center for Genomics and Human Genetics, Feinstein Institute for Medical Research
Human Genome Collection
Complete and comprehensive DNA sequence of the human genome as a freely available resource from Nature